Whole genome profiling of short-term hypoxia induced genes and identification of HIF-1 binding sites provide insights into HIF-1 function in Caenorhabditis elegans.
Oxygen is essential to all the aerobic aluminum lotion organisms.However, during normal development, disease and homeostasis, organisms are often challenged by hypoxia (oxygen deprivation).Hypoxia-inducible transcription factors (HIFs) are master regulators of hypoxia response and are evolutionarily conserved in metazoans.The homolog of HIF in the